Figure 5.

Effects of the interaction between S100A7 and miR-26b-5p on cell invasion. (A) Invasiveness of iRBE or iHCCC-9810 cells following transfection with a non-sense control, or an miR-25b-5p mimic with a 3′UTR wt or mt S100A7. (B) Invasiveness of RBE and HCCC-9810 cells following transfection with a non-sense control, an miR-26b-5p inhibitor or the inhibitor and shRNA against S100A7. S100A7, S100 calcium-binding protein A7; miR, microRNA; iRBE, invasive subpopulation of RBE cells; iHCCC-9810, invasive subpopulation of HCCC-9810 cells; 3′UTR, 3′ untranslated region; wt, wild-type; mt, mutant; shRNA, short hairpin RNA. NG, P>0.05; **P<0.01; vs. non-sense controls respectively.