Table I.

Mutations in the multi-gene panel (n=46).

Index	Gene name	Var start	Var end	Ref allele	Var allele	Amino acid change
1	MT-ND1	3316	3316	G	A	A-T
2	MT-ND1	3376	3376	G	A	E-K
3	MT-ND1	3394	3394	T	C	Y-H
4	MT-ND1	3460	3460	G	A	A-T
5	MT-ND1	3497	3497	C	T	A-V
6	MT-ND1	3571	3571	C	T	L-F
7	MT-ND1	3635	3635	G	A	S-N
8	MT-ND1	3700	3700	G	A	A-T
9	MT-ND1	3733	3733	G	A	E-K
10	MT-ND1	3866	3866	T	C	I-T
11	MT-ND1	4025	4025	C	T	T-M
12	MT-ND1	4171	4171	C	A	L-M
13	MT-ND1	4216	4216	T	C	Y-H
14	MT-ND2	4640	4640	C	A	I-M
15	MT-ND2	5244	5244	G	A	G-S
16	MT-ATP6	9101	9101	T	C	I-T
17	MT-CO3	9804	9804	G	A	A-T
18	MT-ND3	10237	10237	T	C	I-T
19	MT-ND4L	10663	10663	T	C	V-A
20	MT-ND4L	10680	10680	G	A	A-T
21	MT-ND4	11253	11253	T	C	I-T
22	MT-ND4	11696	11696	G	A	V–I
23	MT-ND4	11778	11778	G	A	R-H
24	MT-ND5	12338	12338	T	C	M-T
25	MT-ND5	12811	12811	T	C	Y-H
26	MT-ND5	12848	12848	C	T	A-V
27	MT-ND5	13051	13051	G	A	G-S
28	MT-ND5	13528	13528	A	G	T-A
29	MT-ND5	13637	13637	A	G	Q-R
30	MT-ND5	13730	13730	G	A	G-E
31	MT-ND6	14279	14279	G	A	S-L
32	MT-ND6	14325	14325	T	C	N-D
33	MT-ND6	14482	14482	C	A	M-I
34	MT-ND6	14482	14482	C	G	M-I
35	MT-ND6	14484	14484	T	C	M-V
36	MT-ND6	14495	14495	A	G	L-S
37	MT-ND6	14498	14498	T	C	Y-C
38	MT-ND6	14502	14502	T	C	I–V
39	MT-ND6	14568	14568	C	T	G-S
40	MT-ND6	14596	14596	A	T	I-M
41	MT-CYB	14831	14831	G	A	A-T
42	MT-CYB	15812	15812	G	A	V-M
43	MT-TM	4435	4435	A	G	tRNAMet
44	MT-TT	15951	15951	A	G	tRNAThr
45	MT-TE	14693	14693	A	G	tRNAGlu
46	MT-TE	14727	14727	T	C	tRNAGlu

Var start, start site of variant; var end, end site of variant; ref allele, referenced allele; Var allele, variant allele.