Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 8;15(1):1313–1318. doi: 10.3892/ol.2017.7367

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018, Spandidos Publications

PMC Copyright notice

Figure 2. — Ang1 induces PTC proliferation and migration via activating Tie2. (A) pcDNA3.1-Ang1 transfection upregulated Ang1 expression. (B) Tie2 shRNA silenced Tie2 expression. (C) An MTT assay was utilized to analyze the effect of Ang1 and Tie-2 on the proliferation of PTC cells. (D) A wound-healing assay was used to analyze the effect of expression Ang1 and Tie-2 on the migration of PTC cells. Ang1 group, PTC cells transfected with pcDNA3.1-Ang1. Tie2 shRNA group, PTC cells transfected with Tie2 shRNA. Data are presented as the mean ± standard deviation from three independent experiments. *P<0.01 vs. control group. Ang1, angiopoietin 1; Tie2, Ang receptor; PTC, papillary thyroid carcinoma; shRNA, short hairpin RNA.