(+)-Strebloside induces apoptosis in OVCAR3 cells. (A) Western blot of OVCAR3 cell lysates treated with (+)-strebloside and digitoxin were probed for PARP, caspase 3, cleaved caspase3, and actin. (B and C) Quantitative densitometry of western blots indicated increased expression of cleaved PARP and cleaved caspase 3 in OVCAR3 cells (n = 3). (D and E) Western blotting of OVCAR3 cell lysates treated with (+)-strebloside or digitoxin were probed for Mcl-1, Bcl-xL and actin. (F and G) Quantitative densitometry of western blots indicated decreased expression of Mcl-1 OVCAR3 cells (n = 3. * p ≤0.05, ** p ≤0.01).