Table 3.
List of ASC-associated genes from RNA-Seq that contain potential ISRE and/or IRF-E sites in their regulatory regions.a
| Gene | Chromosome position (Hg19) | ISRE | IRF-E |
|---|---|---|---|
| PRDM1 | chr6:106,534,195-106,557,814 | 106566840, 106547222 | 106562388 |
| XBP1 | chr22:29,190,548-29,196,560 | ND | ND |
| IRF4 | chr6:391,739-411,443 | 391724 | 409414 |
| IRF5 | chr7:128,577,994-128,590,088 | 128580725 | 128594612 |
| PAX5 | chr9:36,838,531-37,034,476 | ND | 36867441, 36868076, 37197361 |
| AICDA | chr12:8,754,762-8,765,442 | ND | ND |
| CD38 | chr4:15,779,931-15,850,706 | ND | ND |
| BTK | chrX:100,604,435-100,641,212 | ND | 100668558 |
| LYN | chr8:56,792,386-56,925,006 | 56842848, 56863323 | 6773360, 56793604 |
| BLK | chr8:11,351,521-11,422,108 | ND | 11349703 |
| IKZF1 | chr7:50,344,378-50,472,798 | 50340355, 50484586 | 50424402, 50444411, 50484587 |
| IKZF2 | chr2:213,864,411-214,015,058 | 213831888, 214030738, 214014429, 214017464, 214030738 | 213936673, 214015411, 214017463 |
| STAT3 | chr17:40,465,343-40,540,513 | 40460528 | ND |
| STAT4 | chr2:191,894,302-192,016,322 | ND | 191885173, 191964289 |
| MYC | chr8:128,748,315-128,753,680 | ND | ND |
| MKI67 | chr10:129,894,925-129,924,468 | ND | ND |
| IL6 | chr7:22,766,766-22,771,621 | ND | 22763062, 22765259 |
| IL12A | chr3:159,706,623-159,713,806 | ND | ND |
| NFKB1 | chr4:103,422,486-103,538,459 | 103424172, 103560981 | 103448890, 103459016, 103533964 |
| RELA | chr11:65,421,067-65,430,443 | ND | 65431520 |
| RELB | chr19:45,504,707-45,541,456 | ND | ND |
| CASP5 | chr11:104,864,967-104,893,895 | ND | ND |
aConsensus sequences were identified through UCSC using Hg19 and transcription factor binding sites that are within 4 kb upstream of the transcription start site (TSS) and 4 kb downstream of the stop codon.
ND, not detected.