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. 2018 Jan 11;12:137–148. doi: 10.2147/DDDT.S148457

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© 2018 Han et al. This work is published and licensed by Dove Medical Press Limited

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Chemical structural formula of IP. (A) Proliferative responses and osteogenic differentiation of hPDLCs stimulated with IP. (B) Proliferation of hPDLCs stimulated with IP for 24 hours by CCK-8 assay. (C) The growth curve of the control group (0 M) and the IP group (10⁻⁷ M). (D) ALP activity quantification of hPDLCs stimulated with IP for 7 and 14 days and blank control was used to prove the effect of the osteogenic inducing fluid. *P<0.05, **P<0.01, ***P<0.001 versus control; mean ± SD (n$3).

Abbreviations: IP, ipriflavone; hPDLCs, human periodontal ligament cells; CCK-8, cell counting kit-8; ALP, alkaline phosphatase; SD, standard deviation; OD, optical density.