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Expression of ALP, Runx2, GPR30 were all increased by IP in both protein level (A) and mRNA level (B). The PI3K/AKT signaling pathway was activated by IP because the p-AKT expression was high without the increase of total AKT (C). **P<0.01, ***P<0.001.
Abbreviations: IP, ipriflavone; ALP, alkaline phosphatase.
