Table 3.

Examining the influence of relevant demographic and clinical covariables on the associations between cytokine/receptors and cognitive tests. Results for independent multivariable linear regression models.

Test measure (Outcome)	Cytokine or Soluble Receptor	Crude		Age and Education Adjusted¹		Stage Adjusted²		Anthracycline Adjusted		Age, Education, Stage, and Anthracycline Adjusted¹^,²
		β	p-value	β	p-value	β	p-value	β	p-value	β	p-value
Delayed Matching to Sample
Percent Correct	sTNFRI	−34.84	0.029	−25.30	0.194	−38.18	0.033	−35.11	0.038	−28.80	0.202
Percent Correct All Delays	sTNFRI	−45.72	0.025	−34.39	0.172	−48.90	0.033	−44.05	0.042	−37.44	0.208
Percent Correct 12s Delay	sTNFRI	−83.59	0.001	−89.91	0.006	−87.11	0.002	−83.67	0.002	−92.06	0.018
Percent Correct 12s Delay	sTNFRII	−64.82	0.006	−61.77	0.028	−63.68	0.011	−63.72	0.009	−62.57	0.065
Mean Correct Latency 4s Delay	MCP-1	−573.54	0.015	-738.72	0.026	−548.45	0.052	-599.83	0.024	−725.85	0.063
Rapid Visual Information Processing
Total Misses	TNF-α	−3.87	0.049	-4.61	0.026	−3.57	0.086	−1.67	0.276	−2.29	0.393
Probability of detecting a Target	TNF-α	0.040	0.037	0.047	0.024	0.039	0.054	0.021	0.193	0.03	0.258
One Touch Stockings of Cambridge
Problems Solved on the First Choice	MCP-1	1.43	0.036	2.11	0.030	1.09	0.189	1.94	0.008	1.67	0.109
Mean Choices to Correct	MCP-1	−0.146	0.033	−0.235	0.014	−0.137	0.104	−0.201	0.006	−0.20	0.059

Age: age at enrollment,

Stage categorized as stage 4, stage 3, and stage 1 or 2.