Table 2. Univariate and multivariate analysis for factors related to overall survival using the COX proportional hazard model.

Variables		Univariate analysis			Multivariate analysis
		P	HR	95%CI	P	HR	95%CI
Age	44.027±15.926	0.470	1.007	0.989-1.025	N.A
Gender	female vs male	0.477	1.231	0.694-2.181	N.A
Lymph node metastasis	No vs Yes	0.330	0.752	0.424-1.335	N.A
Distant metastasis	No vs Yes	0.767	1.090	0.615-1.934	N.A
TNM stage	I + II vs III + IV	0.007	0.397	0.202-0.779	0.184	0.622	0.309-1.253
Largest tumor dimension	<3 vs ≥3	0.156	0.658	0.368-1.174	N.A
Lymphatic invasion	No vs Yes	0.204	1.460	0.814-2.617	N.A
Vascular invasion	No vs Yes	0.878	0.956	0.540-1.695	N.A
Perineural invasion	No vs Yes	0.797	1.078	0.608-1.911	N.A
XIST expression	high vs low	<0.001	3.727	1.964-7.072	0.001	3.336	1.686-6.601