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. Author manuscript; available in PMC: 2018 Jan 15.
Published in final edited form as: Adv Anat Embryol Cell Biol. 2017;223:171–193. doi: 10.1007/978-3-319-53168-7_8

Fig. 8.3.

Fig. 8.3

Three possible links between capsid and envelope. Capsids acquire lipid envelopes by budding into intracellular membranes derived from the secretory/recycling pathways. Capsid interactions with lipid membranes are indirect and dependent upon tegument and envelope proteins. Depicted are three proposed linkages with varying degrees of support in the literature. Two tegument proteins that directly bind capsids are featured: pUL16 and pUL36 (VP1/2). Tegument proteins are indicated by their unique long gene number (i.e., UL11 is labeled as 11)