Table 1.
Patient Characteristics
| Variable | Non-Cases, n (Column %) | HO-CDI Cases, n (Column %) | Univariate P-Value |
|---|---|---|---|
| Total n | 77,757 | 323 | |
| Demographics | |||
| Age <65 | 35,331 (45.4) | 84 (26.0) | <0.0001 |
| 65-84 | 32,776 (42.2) | 187 (57.9) | |
| >84 | 9,650 (12.4) | 52 (16.1) | |
| Female | 42,225 (54.3) | 173 (53.6) | 0.789 |
| Male | 35,532 (45.7) | 150 (46.4) | |
| Medicaid | 4,695 (6.0) | 15 (4.6) | 0.0004 |
| Medicare | 29,201 (37.6) | 156 (48.3) | |
| Other payers | 43,861 (56.4) | 152 (47.1) | |
| Previous Healthcare Exposure | |||
| Transferred from other acute care hospital | 4,057 (5.2) | 35 (10.8) | <0.0001 |
| Transferred from skilled nursing facilities | 1,919 (2.5) | 42 (13.0) | <0.0001 |
| Same hospital discharge during previous 30 days | 9,916 (12.8) | 94 (29.1) | <0.0001 |
| CDI during previous hospitalization | 306 (0.4) | 10 (3.1) | <0.0001 |
| NIM in previous hospitalization | 1,144 (1.5) | 11 (3.4) | 0.0041 |
| CIM in previous hospitalization | 3,174 (4.1) | 29 (9.0) | <0.0001 |
| Clinical Presentation at Admission | |||
| Admitted to intensive care unit | 12,452 (16.0) | 115 (35.6) | <0.0001 |
| Mechanic ventilation on admission | 2,268 (2.9) | 52 (16.1) | <0.0001 |
| CIM on admission | 8,570 (11.0) | 82 (25.4) | <0.0001 |
| Albumin <= 2.4 g/dL | 2,123 (2.7) | 36 (11.1) | <0.0001 |
| Albumin 2.5 - 2.7 g/dL | 1,822 (2.3) | 30 (9.3) | |
| Albumin 2.8 - 3 g/dL | 3,126 (4.0) | 39 (12.1) | |
| Albumin <= 3 g/dL | 7,071 (9.1) | 105 (32.5) | <0.0001 |
| Creatinine > 2.0 mg/dL | 6,280 (8.1) | 72 (22.3) | <0.0001 |
| Pro BNP > 8000 | 104 (0.1) | 4 (1.2) | <0.0001 |
| Bands > 32% | 886 (1.1) | 16 (5.0) | <0.0001 |
| Platelets <= 115 10^9/L | 5,590 (7.2) | 44 (13.6) | <0.0001 |
| Platelets 115.1 - 150 10^9/L | 5,539 (7.1) | 41 (12.7) | |
| Platelets > 420 10^9/L | 3,191 (4.1) | 27 (8.4) | |
| Platelets <=150 or >420 10^9/L | 14,320 (18.4) | 112 (34.7) | <0.0001 |
| WBC 11 - 14.1 ×1,000/mm3 | 12,010 (15.4) | 72 (22.3) | <0.0001 |
| WBC 14.2 - 19.8 ×1,000/mm3 | 8,169 (10.5) | 59 (18.3) | |
| WBC 1>19.8 ×1,000/mm3 | 4,092 (5.3) | 36 (11.1) | |
| WBC > 11 ×1,000mm3 | 24,271 (31.2) | 167 (51.7) | <0.0001 |
| Troponin I >0.1 or CPK MB >=6 ng/mL | 6,863 (8.8) | 54 (16.7) | <0.0001 |
| Community-Onset CDI Pressure, per 10,000 admissions, median (1st, 3rd quartile) | 19.3 (0, 38.9) | 20.9 (0, 41.6) | 0.2551 |
| All Community-Onset CDI Pressure, per 10,000 admissions, median (1st, 3rd quartile) | 52.7 (27.4, 85.7) | 59.5 (30.7, 94.0) | 0.0499 |
Note: NIM: nosocomial infection marker; CIM: community infection marker; WBC: white blood cell count