Table 2.
Hospital-onset Clostridium difficile Infection Risk Score Model
| Variable | Model with CO-CDI pressure | Model with All-CO-CDI pressure | ||||||
|---|---|---|---|---|---|---|---|---|
| Estimate (SE) | aOR (95%CI) | P value | Score | Estimate (SE) | aOR (95%CI) | P value | Score | |
| CO-CDI pressure > 60th percentile* | 0.23 (0.12) | 1.26 (1.00,1.59) | 0.0534 | 1 | 0.45 (0.19) | 1.56 (1.07,2.27) | 0.0201 | 2 |
| Age ≥65 | 0.65 (0.14) | 1.92 (1.47,2.51) | <.0001 | 3 | 0.65 (0.14) | 1.91 (1.46,2.49) | <.0001 | 3 |
| Transferred from other acute care hospital | 0.57 (0.20) | 1.77 (1.20,2.62) | 0.0041 | 3 | 0.57 (0.20) | 1.77 (1.20,2.62) | 0.004 | 3 |
| Transferred from skilled nursing facilities | 0.96 (0.18) | 2.61 (1.82,3.75) | <.0001 | 4 | 0.94 (0.18) | 2.57 (1.79,3.68) | <.0001 | 4 |
| Mechanic ventilation on admission | 0.90 (0.19) | 2.47 (1.70,3.60) | <.0001 | 4 | 0.91 (0.19) | 2.49 (1.71,3.63) | <.0001 | 4 |
| Admitted to intensive care unit | 0.43 (0.15) | 1.54 (1.16,2.05) | 0.003 | 2 | 0.43 (0.15) | 1.54 (1.16,2.05) | 0.0029 | 2 |
| Hospital discharge during previous 30 days | 0.64 (0.14) | 1.89 (1.44,2.48) | <.0001 | 3 | 0.64 (0.14) | 1.89 (1.44,2.49) | <.0001 | 3 |
| CIM on admission | 0.44 (0.15) | 1.55 (1.17,2.06) | 0.0025 | 2 | 0.44 (0.15) | 1.56 (1.17,2.07) | 0.0023 | 2 |
| CDI during previous hospitalization | 1.18 (0.36) | 3.25 (1.61,6.57) | 0.001 | 5 | 1.18 (0.36) | 3.24 (1.60,6.55) | 0.0011 | 5 |
| Albumin ≤ 3 g/dL | 0.80 (0.14) | 2.23 (1.70,2.93) | <.0001 | 4 | 0.80 (0.14) | 2.22 (1.69,2.91) | <.0001 | 4 |
| Creatinine > 2.0 mg/dL | 0.45 (0.15) | 1.57 (1.17,2.10) | 0.0027 | 2 | 0.46 (0.15) | 1.58 (1.18,2.12) | 0.0022 | 2 |
| Bands > 32% | 0.67 (0.27) | 1.96 (1.15,3.34) | 0.0136 | 3 | 0.69 (0.27) | 1.98 (1.16,3.38) | 0.0117 | 3 |
| Platelets ≤150 or >420 10^9/L | 0.49 (0.13) | 1.63 (1.28,2.09) | 0.0001 | 2 | 0.48 (0.13) | 1.62 (1.26,2.07) | 0.0001 | 2 |
| WBC > 11 ×1,000mm3 | 0.41 (0.12) | 1.50 (1.18,1.91) | 0.0009 | 2 | 0.40 (0.12) | 1.49 (1.17,1.89) | 0.0012 | 2 |
*
CO-CDI Pressure was dichotomized at 60th percentile (>24.8 CO-CDI per 10,000 admissions); All-CO-CDI Pressure was dichotomized at 60th percentile (>64.1 of all CO-CDI per 10,000 admissions).