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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: J Pharm Sci. 2017 Oct 12;107(2):690–697. doi: 10.1016/j.xphs.2017.10.005

Figure 2. In vitro versus in vivo release studies.

Figure 2

In vitro versus in vivo percent cumulative release of 5-FU from 5-FU-loaded PLGA pellets (50% w/w). The in vivo release study was performed twice with the use of 5 pellets per time point. In this experiment, in vivo release was faster than in vitro release. Complete release of 5-FU from pellets occurred within two weeks of the pellets being implanted in mice. A strong correlation existed between the in vitro and in vivo release (Pearson correlation coefficient = 0.98, p < 0.01)