Figure 7. Survival curve of CT26-challenged mice treated with 5-FU-loaded pellets.
BALB/CJ mice were challenged with CT26 cells and then once palpable tumor was detectable (Day 5) the mice were treated with the indicated formulation. Kaplan-Meier estimator was used to analyze survival of mice. The log-rank test with Tukey adjustment was used for multiple comparison. Events were death from all causes. * and † designate group was statistically different from the untreated group and mice treated with soluble 5-FU (IP), respectively (p < 0.05).