TABLE 4.
Geometric mean sexual functioning score by post-diagnostic Mediterranean Diet Score and dietary components among 2960 men with prostate cancer, stratified by erectile dysfunction prior to prostate cancer diagnosis*
| Men without ED prior to prostate cancer diagnosis (n=2126) | ||||||
|---|---|---|---|---|---|---|
| Mediterranean Diet Score | 0-3 | 4-5 | 6-9 | p trend | ||
| 35 (4) | 35 (4) | 35 (4) | 0.71 | |||
| Dietary components, by quintile | ||||||
| Dietary components | 1 | 2 | 3 | 4 | 5 | p trend |
| Legume | 36 (4) | 35 (4) | 32 (4) | 36 (4) | 36 (4) | 0.81 |
| Fruit | 35 (4) | 35 (4) | 37 (4) | 34 (4) | 34 (4) | 0.51 |
| Total Dairy | 37 (4) | 33 (4) | 34 (4) | 34 (4) | 37 (4) | 0.78 |
| Fish | 35 (4) | 35 (4) | 34 (4) | 34 (4) | 37 (4) | 0.15 |
| Vegetable | 35 (4) | 32 (4) | 35 (4) | 35 (4) | 37 (4) | 0.17 |
| Cereal | 36 (4) | 36 (4) | 33 (4) | 33 (4) | 36 (4) | 0.70 |
| Total Meat | 36 (4) | 34 (4) | 32 (4) | 37 (4) | 35 (4) | 0.82 |
| Alcohol | 35 (4) | 36 (4) | 35 (4) | 34 (4) | 35 (4) | 0.69 |
| Poly:Saturated Fat | 36 (4) | 35 (4) | 32 (4) | 35 (4) | 37 (4) | 0.25 |
| Saturated Fat | 36 (4) | 33 (4) | 34 (4) | 35 (4) | 36 (4) | 0.52 |
| Monounsaturated Fat | 34 (4) | 32 (4) | 36 (4) | 36 (4) | 36 (4) | 0.03 |
| Polyunsaturated Fat | 35 (4) | 35 (4) | 33 (4) | 34 (4) | 38 (4) | 0.05 |
| Men with ED prior to prostate cancer diagnosis (n=834) | ||||||
| Mediterranean Diet Score | 0-3 | 4-5 | 6-9 | p trend | ||
| 22 (4) | 23 (5) | 25 (5) | 0.11 | |||
| Dietary components, by quintile | ||||||
| Dietary components | 1 | 2 | 3 | 4 | 5 | p trend |
| Legume | 21 (5) | 24 (5) | 23 (5) | 25 (5) | 23 (5) | 0.26 |
| Fruit | 22 (5) | 22 (5) | 23 (5) | 24 (5) | 22 (5) | 0.85 |
| Total Dairy | 22 (5) | 20 (5) | 25 (5) | 21 (5) | 22 (5) | 0.68 |
| Fish | 20 (5) | 24 (5) | 24 (5) | 20 (5) | 23 (5) | 0.77 |
| Vegetable | 20 (5) | 20 (5) | 26 (5) | 27 (5) | 22 (5) | 0.10 |
| Cereal | 21 (5) | 21 (5) | 25 (5) | 20 (5) | 24 (5) | 0.26 |
| Total Meat | 24 (5) | 20 (5) | 25 (5) | 24 (5) | 21 (5) | 0.71 |
| Alcohol | 23 (5) | 20 (5) | 23 (5) | 24 (5) | 24 (5) | 0.30 |
| Poly:Saturated Fat | 22 (5) | 23 (5) | 21 (5) | 23 (5) | 24 (5) | 0.45 |
| Saturated Fat | 20 (5) | 23 (5) | 19 (5) | 24 (5) | 21 (5) | 0.92 |
| Monounsaturated Fat | 20 (5) | 24 (5) | 20 (5) | 23 (5) | 24 (5) | 0.36 |
| Polyunsaturated Fat | 23 (5) | 22 (5) | 21 (5) | 22 (5) | 25 (5) | 0.30 |
Sexual functioning scores relate to symptoms of erectile dysfunction or anorgasmia, and higher scores indicate fewer sexual problems. All values represent geometric mean scores adjusted for age at diagnosis, time since treatment or diagnosis, calories, clinical stage of disease, Gleason score, treatment type, PSA at diagnosis, family history of prostate cancer, and the following covariates were measured at the time of QOL outcome assessment: presence of comorbidities, body mass index, smoking status, walking pace, vigorous physical activity, and any weightlifting (Model 2). Results are stratified by pre-diagnosis erectile dysfunction. P trend was calculated using the median of each quartile modeled continuously and reported by strata.