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BAK1 S-glutathionylation. (a) Structural and functional features of a protein kinase. (b) Structure of glutathione in a mixed disulfide with a cysteine residue. Glutathione consists of a glutamate connected through a γ-peptide bond to a cysteine-glycine dipeptide. BAK1 structures taken from simulation with (c) C353, (d) C374, and (e) C408 glutathionylated. ATP is shown in the ATP-binding pocket for all three systems. To see this figure in color, go online.
