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. 2017 Dec 5;113(11):2406–2414. doi: 10.1016/j.bpj.2017.09.035

Figure 2.

Figure 2

Increasing the osmolarity of pipette solution inhibits slow endocytosis at calyces. (A) Shown here is the averaged ICa and capacitance (Cm, mean + SE) induced by depol20ms (arrow) from calyces (10 calyces, 10 mice) with a control whole-cell pipette solution (mean: 312 mOsm). Note that ICa and Cm are plotted in different timescales. Mean + SE is plotted every 2 ms in the ICa trace, but every 1 s in the Cm trace. (B) Given here is the averaged ICa and Cm (mean + SE) induced by depol20ms (arrow) from calyces (10 calyces, 10 mice) with a whole-cell pipette solution at higher osmolarity (mean: 383 mOsm). (C) Given here is Ratedecay, ΔCm, and QICa induced by depol20ms in mouse calyces with a mean pipette osmolarity of 312 mOsm (control, 10 calyces for Ratedecay measurements) or 383 mOsm (10 calyces for Ratedecay measurements) in the whole-cell pipette solution. ∗∗p < 0.01 (t-test in comparison with control group).