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. 2018 Jan 11;8:1944. doi: 10.3389/fimmu.2017.01944

Table 2.

Cohort study: results of logistic regression models examining the non-specific markers of inflammation (NSMI) as indicators of recent (2–3 months) parasite exposure after accounting for body condition, sex, age, season, and animal id.

NSMI Pathogen β SE Test statistic FDR sig level p-Value
log2 (Haptoglobin)
Bovine herpes virus (BHV) −0.06307 0.038 −1.66 0.021 0.09695
PI-3 0.12049 0.03749 3.214 0.007 0.00131
Bovine respiratory syncytial virus (BRSV) −0.05834 0.05671 −1.029 0.043 0.655834
Bovine diarrhea virus (BVDV) −0.03116 0.03953 −0.788 0.029 0.4309
AD-3 0.01374 0.03651 0.376 0.05 0.707
Mycoplasma bovis (MB) 0.19008 0.0598 3.178 0.014 0.00148
Mannheimia hemolytica (MH) −0.02125 0.03593 −0.592 0.036 0.55414

log2 (Serum amyloid A)
BHV −0.04368 0.02235 −1.954 0.007 0.0507
PI-3 0.003432 0.019632 0.175 0.05 0.86123
BRSV −0.03458 0.03394 −1.019 0.036 0.308322
BVDV −1.32E–01 8.95E−02 −1.471 0.029 0.14131
AD-3 0.01316 0.02144 0.614 0.043 0.53946
MB 0.3577 0.19031 1.88 0.014 0.060174
MH −0.04644 0.02661 −1.745 0.021 0.0809

TNF-α
BHV −0.19076 0.3101 −0.615 0.036 0.5384
PI-3 −0.32148 0.26095 −1.232 0.007 0.21798
BRSV −0.62706 71187 −0.881 0.021 0.378
BVDV −0.24408 0.35926 −0.679 0.029 0.496886
AD-3 −0.099964 0.212616 −0.47 0.043 0.638
MB 0.277238 0.22845 1.192 0.014 0.233131
MH −0.064314 0.235515 −0.273 0.05 0.784793

IFNγ
BHV −0.77378 0.58834 −1.315 0.029 0.18844
PI-3 0.20225 0.18011 1.123 0.043 0.26148
BRSV −3.63397 2.19124 −1.658 0.021 0.0972
BVDV 0.17317 0.1457 1.189 0.036 0.234609
AD-3 0.34937 0.18254 1.914 0.014 0.0556
MB −2.23E+00 1.03E + 00 −2.157 0.007 0.031
MH 0.26631 0.29246 0.125 0.05 0.900229

FDR significance levels are false discovery rate significance levels, which avoid issues for false positives that can occur when using multiple testing procedures.

Bold values indicate statistically significant relationships.