Table 2.
Cohort study: results of logistic regression models examining the non-specific markers of inflammation (NSMI) as indicators of recent (2–3 months) parasite exposure after accounting for body condition, sex, age, season, and animal id.
| NSMI | Pathogen | β | SE | Test statistic | FDR sig level | p-Value |
|---|---|---|---|---|---|---|
| log2 (Haptoglobin) | ||||||
| Bovine herpes virus (BHV) | −0.06307 | 0.038 | −1.66 | 0.021 | 0.09695 | |
| PI-3 | 0.12049 | 0.03749 | 3.214 | 0.007 | 0.00131 | |
| Bovine respiratory syncytial virus (BRSV) | −0.05834 | 0.05671 | −1.029 | 0.043 | 0.655834 | |
| Bovine diarrhea virus (BVDV) | −0.03116 | 0.03953 | −0.788 | 0.029 | 0.4309 | |
| AD-3 | 0.01374 | 0.03651 | 0.376 | 0.05 | 0.707 | |
| Mycoplasma bovis (MB) | 0.19008 | 0.0598 | 3.178 | 0.014 | 0.00148 | |
| Mannheimia hemolytica (MH) | −0.02125 | 0.03593 | −0.592 | 0.036 | 0.55414 | |
| log2 (Serum amyloid A) | ||||||
| BHV | −0.04368 | 0.02235 | −1.954 | 0.007 | 0.0507 | |
| PI-3 | 0.003432 | 0.019632 | 0.175 | 0.05 | 0.86123 | |
| BRSV | −0.03458 | 0.03394 | −1.019 | 0.036 | 0.308322 | |
| BVDV | −1.32E–01 | 8.95E−02 | −1.471 | 0.029 | 0.14131 | |
| AD-3 | 0.01316 | 0.02144 | 0.614 | 0.043 | 0.53946 | |
| MB | 0.3577 | 0.19031 | 1.88 | 0.014 | 0.060174 | |
| MH | −0.04644 | 0.02661 | −1.745 | 0.021 | 0.0809 | |
| TNF-α | ||||||
| BHV | −0.19076 | 0.3101 | −0.615 | 0.036 | 0.5384 | |
| PI-3 | −0.32148 | 0.26095 | −1.232 | 0.007 | 0.21798 | |
| BRSV | −0.62706 | 71187 | −0.881 | 0.021 | 0.378 | |
| BVDV | −0.24408 | 0.35926 | −0.679 | 0.029 | 0.496886 | |
| AD-3 | −0.099964 | 0.212616 | −0.47 | 0.043 | 0.638 | |
| MB | 0.277238 | 0.22845 | 1.192 | 0.014 | 0.233131 | |
| MH | −0.064314 | 0.235515 | −0.273 | 0.05 | 0.784793 | |
| IFNγ | ||||||
| BHV | −0.77378 | 0.58834 | −1.315 | 0.029 | 0.18844 | |
| PI-3 | 0.20225 | 0.18011 | 1.123 | 0.043 | 0.26148 | |
| BRSV | −3.63397 | 2.19124 | −1.658 | 0.021 | 0.0972 | |
| BVDV | 0.17317 | 0.1457 | 1.189 | 0.036 | 0.234609 | |
| AD-3 | 0.34937 | 0.18254 | 1.914 | 0.014 | 0.0556 | |
| MB | −2.23E+00 | 1.03E + 00 | −2.157 | 0.007 | 0.031 | |
| MH | 0.26631 | 0.29246 | 0.125 | 0.05 | 0.900229 | |
FDR significance levels are false discovery rate significance levels, which avoid issues for false positives that can occur when using multiple testing procedures.
Bold values indicate statistically significant relationships.