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Most significant metabolic differences between glucose 6-phosphate dehydrogenase (G6PD) sufficient and deficient red blood cells (RBCs). Panels indicate alterations to sulfur/one-carbon metabolism (A–E), purine oxidation (F), glutathione homeostasis (G,H), and carboxylates (I) in G6PD sufficient (blue line) and deficient (red line) RBCs during storage in the blood bank (median + ranges are shown in light blue or red for both G6PD sufficient and deficient groups, respectively).
