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. 2018 Jan 11;8:1974. doi: 10.3389/fimmu.2017.01974

Figure 3.

Figure 3

Oxidative stress parameters and lipid peroxidation in isolated peripheral blood neutrophils and mononuclear cells of mild Alzheimer’s disease (mAD) and Alzheimer’s disease (AD) patients, as well as of adult and elderly healthy subjects. Intracellular reduced glutathione (GSH) contents (nmol/mg protein) in neutrophils (A) and lymphocytes (B); intracellular oxidized glutathione (GSSG) contents (nmol/mg protein) in neutrophils (C) and lymphocytes (D); GSSG/GSH ratios in neutrophils (E) and lymphocytes (F); and intracellular malondialdehyde (MDA) contents (nmol/mg protein) in neutrophils (G) and lymphocytes (H). Data are shown as the mean (horizontal bar) of 9–12 values corresponding to the number of subjects analyzed in each group (9 adult, 10 elderly, 11 mAD, and 12 AD). Each value is the mean of duplicate assays. a: P < 0.05 and aa: P < 0.01 with respect to the value in adult subjects; b: P < 0.05 and bb: P < 0.01 with respect to the value in elderly subjects; and c: P < 0.05 with respect to the value in mAD patients.