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. 2018 Jan 11;8:1974. doi: 10.3389/fimmu.2017.01974

Table 2.

Stimulation of proliferation (%) in response to phytohemagglutinin and lipopolysaccharide (1 µg/mL), in isolated peripheral mononuclear cells of adult and elderly healthy subjects, as well as of mild Alzheimer’s disease (mAD) and severe Alzheimer’s disease (AD) patients.

Lymphoproliferation (% stimulation) Adult Elderly mAD AD
PHA (%) 1,950 ± 232 391 ± 56a 198 ± 19a,b 218 ± 36a,c
LPS (%) 346 ± 25 176 ± 13d 156 ± 12c,e 167 ± 17e

Data are expressed as mean ± SD of the values corresponding to 20 adult, 38 elderly, 26 mAD, and 18 AD subjects. Each value is the mean of duplicate assays.

aP < 0.001 with respect to the value in adult subjects.

bP < 0.01 with respect to the value in elderly subjects.

cP < 0.05 with respect to the value in elderly subjects.

dP < 0.05 with respect to the value in adult subjects.

eP < 0.01 with respect to the value in adult subjects.