Table 3.

Levels of interleukin (IL)-6 and tumor necrosis factor (TNF)-α (pg/mL) released by peripheral whole blood cells of adult and elderly healthy subjects, as well as of mild Alzheimer’s disease (mAD) and severe Alzheimer’s disease (AD) patients, after 4 h of culture in basal conditions.

Basal cytokines	Adult	Elderly	mAD	AD
IL-6 (pg/mL)	8.89 ± 1.93	16.23 ± 4.72a	16.21 ± 3.84a	21.60 ± 5.17b,c,d
TNF-α (pg/mL)	24.76 ± 6.14	40.30 ± 14.89e	90.76 ± 26a,c	105.8 ± 22.5a,c

Data are expressed as mean ± SD of the values corresponding to 10 adult, 10 elderly, 8 mAD, and 8 AD subjects. Each value is the mean of duplicate assays.

^aP < 0.01 with respect to the value in adult subjects.

^bP < 0.001 with respect to the value in adult subjects.

^cP < 0.05 with respect to the value in elderly subjects.

^dP < 0.05 with respect to the value in mAD patients.

^eP < 0.05 with respect to the value in adult subjects.