Table 4.

OEC-seeded biomaterial SCI studies.

SCI model	Biomaterial	Cell type	Outcome	References
Rat T11/T12 dorsal hemisection	2 mm poly(D,L)-lactide biomatrix (Category II and IV)	OEC/ONF within and 1 mm rostrocaudal injections	Migration of cells up to but not within biomatrix, poor cell survival within biomatrix, increased axonal growth excluding CST, increased stride length and swing speed	Deumens et al., 2006a
Rat T13 unilateral hemisection	2 mm collagen-based multi-channel 3D matrices (Category II)	OEC	No improvement in CatWalk gait analysis or alleviation of allodynia	Deumens et al., 2013
Rat T9/T10 complete transection	2 mm PLGA scaffolds (Category II)	OEC	Increased BBB score and crossing of inclined plane, increased axonal preservation, decreased astrogliosis	Wang et al., 2017