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. 2018 Jan 15;8:757. doi: 10.1038/s41598-018-19158-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Bidirectional cross-species sRNA-mediated gene regulation during the compatible interaction. The hive plot indicates the interactions between P. viticola sRNAs originating from either intergenic (yellow dots) or protein coding genes (gray dots) and V. vinifera genes (blue dots). Reciprocally, V. vinifera sRNAs processed from either noncoding RNA (green dots), intergenic regions (purple dots) or resistance genes (red dots) target P. viticola transcripts (yellow dots). The thickness and color intensity of the yellow and blue lines representing the sRNA-target interactions are proportional to the log transformed p-value calculated for the number of reads from the degradome whose 5′ end corresponds (±1) to the expected sRNA-mediated cleavage site: the larger the edge, the more significant the interaction. The color code is different for regulation starting (from light to dark blue) or arriving at P. viticola (from yellow to red). The size of the dots corresponds to the number of regulations identified for a certain sRNA.