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. 2018 Jan 15;8:752. doi: 10.1038/s41598-017-19023-0

Figure 4.

Figure 4

Motor cortex stimulation with different interphase gaps (Exp. 1, Phase II (A,B) and Phase III (C,D)). (A) Shows the effect of interphase gap duration within a biphasic pulse on normalized limb displacement for one subject. In this rat, introducing a 50 µs interphase gap (IPG50) produced a larger limb displacement when compared to a biphasic pulse with no interphase gap (BP). Increasing the interphase gap to 100 µs (IPG100) only led to a small increase in limb displacement. Further increase in interphase gap to 200 and 400 µs (IPG200, IPG400) did not lead to further increases in limb displacement. (B) These findings are reflected in the data at the group level (n = 5). (C) Shows the effect of interphase gap duration within a pseudomonophasic pulse on normalized limb displacement for one individual rat. In this rat, introducing a 50 µs interphase gap (PM_IPG50) produced only a very small increase in limb displacement when compared to a pseudomonophasic pulse with no interphase gap (PM). Further increases in interphase gap to 100, 200 and 400 µs (PM-IPG100, PM-IPG200, PM-IPG400) did not lead to further increases in limb displacement. (D) These findings are reflected in the data at the group level (n = 5). Data are shown as means ± SD. **p < 0.01, ***p < 0.001. Abbreviations: BP = biphasic, IPG = interphase gap, PM = pseudomonophasic.