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. 2018 Jan 15;8:723. doi: 10.1038/s41598-018-19248-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Identification of colonic IL-1R1-expressing cell types. (a) A representative collage image of colonic sections from IL-1R1^GR/GR mice. (b–d) Immunofluorescence labeling of tdTomato (b–d), CD31 (b) and gp38 (c) in the colonic sections from IL-1R1^GR/GR mice, and GFP (d) in colonic sections from CX3CR1GFP-IL-1R1^GR/GR mice. Dashed square marks the area shown at higher magnification on the bottom right. Scale bar, 100 µm.