Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan 15;8:744. doi: 10.1038/s41598-018-19182-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Expression of metabolic targets in DLBCL. RNA expression analysis of metabolic genes involved in glucose metabolism (G6pase, GLUT1, GLUT4, SGLT1, HK2, LDHA, PDHEA1, PDHB); oxidative phosphorylation (Cyt-C, ATPsynthase F, COXII, COXIII, OGDG, SGDH); Lipid metabolism (CS, ACLY, ACC, FAS); PPP (G6PDH, TALDO1,TKT) in DLBCL cell lines and primary B cells obtained from a malignant diffuse B cell lymphoma patient or from a normal spleen tissue. (A) DLBCL cell lines found to exhibit an OxPhos phenotype along with increase in glucose metabolism genes (B) DLBCL cell lines with an increase in glucose transporters and a non-OxPhos phenotype. RNA expression in primary B cells is shown in (C) (top panel, normal B cell and bottom panel, diffuse large B cell). The expression of respective genes was normalized to GAPDH expression. Values are presented as n = 3 ± SD. Asterisks define significant differences p < 0.05.