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. 2018 Jan 15;8:791. doi: 10.1038/s41598-017-19133-9

Table 1.

Characteristics of the Study Sample.

Maternal Characteristics Data Available(N) Mean(SDa)/N(%)
Age at Delivery (years) 88 31.5 (4.9)
Education, Tertiary 88 57 (64.8%)
Pre-Pregnancy Body Mass Index (kg/m2) 88 24.0 (4.2)
Any Diabetic or Hypertensive Disorder in Pregnancy (type 1 or gestational diabetes, chronic or gestational hypertension, pre-eclampsia), Yes 88 15 (17.0%)
History of Physician-Diagnosed Mental Disorders Before Pregnancy, Yes 80 13 (16.3%)
Depressive Symptoms
   Trimester-Weighted Mean Score of Center for Epidemiological Studies 86 10.3 (6.0)
Depression Scale Depressive Symptoms during Pregnancy
   Trimester-Weighted Mean Score of Center for Epidemiological Studies 86 14 (16.3%)
Depression Scale Depressive Symptoms during Pregnancy ≥ 16
   1st Pregnancy Trimester Center for Epidemiological Studies Depression 81 10.2 (6.7)
Scale Depressive Symptom Score
   Mean of 2nd Pregnancy Trimester Center for Epidemiological Studies 86 10.4 (6.5)
Depression Scale Depressive Symptom Scores
   Mean of 3rd Pregnancy Trimester Center for Epidemiological Studies 86 10.3 (6.6)
Depression Scale Depressive Symptom Scores
   Number of Pregnancy Trimesters with Center for Epidemiological Studies 81
     0 53 (65.4%)
     1 16 (19.8%)
     2–3 12 (14.8%)
Beck Depression Inventory-II Score Concurrently to Rating the Child 60 5.9 (5.5)
Placental Morphology
Volume of SMAb-Positive Villi per Placenta (ml) 88 95.1 (50.9)
Volume of Capillaries per SMA-Positive Villi per Placenta (ml) 88 56.0 (35.6)
Volume of SMAb-Negative Villi per Placenta (ml) 88 182.7 (63.9)
Volume of Capillaries per SMAb-Negative Villi per Placenta (ml) 88 157.5 (51.8)
Ratio of the Distribution of SMAb-Positive Villi to SMA-Negative Villi (%) 88 63.7 (56.8)
Villous Barrier Thickness of SMAb-Positive Villi (µm) 88 7.5 (1.7)
Standard Deviation of Villous Barrier Thickness of SMAb-Positive Villi (Variability in Thickness) (µm) 88 6.3 (2.3)
Villous Barrier Thickness of SMAb-Negative Villi (µm) 88 11.9 (4.6)
Standard Deviation of Villous Barrier Thickness of SMAb-Negative Villi (µm) 88 10.2 (5.5)
Placental Weight (grams) 88 589.7 (107.4)
Toddler Characteristics
Gestation Length (weeks) 88 40.3 (1.0)
Sex 88
       Boys 41 (46.6%)
       Girls 47 (53.4%)
Age at Follow-up (months) 60 25.5 (2.9)
Child Behavior Checklist/1½-5 Psychiatric Problems
Total Problems 60 46.8 (9.2)
Internalizing Problems 60 45.4 (8.5)
Externalizing Problems 60 48.6 (9.4)

aSMA = γ-smooth muscle actin. bSD = standard deviation.