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. 2018 Jan 15;8:792. doi: 10.1038/s41598-017-18775-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Relations between heart weight and body weight (panels a and b) and left ventricular weight and body weight (panels c and d). Absolute values of heart Heart weight (HW) and left ventricle weight (LVW), respectively, plotted to body weight (panels a and c). To linearize the formulas HW = 9.97 × BW^0.78 and LVW = 6.00×BW^0.78, the common logarithm was taken: log(HW or LVW) = log(a) + b.log(BW), with the predicted value of exponent b of 0.75 falling well within the 95% confidence limits (panels b and d). This indicates that HW and LVW scale proportionally with body weight according to the natural scaling laws.