Table 1.
Baseline characteristics of all patients.
| Characteristic (n = 73) | No. of patients (%) |
|---|---|
| Age (years) | |
| ≤50 | 55 (75.3) |
| >50 | 18 (24.7) |
| Sex | |
| Male | 39 (53.4) |
| Female | 34 (46.6) |
| Preoperative KPS | |
| 90–100 | 21 (28.8) |
| 70–80 | 52 (71.2) |
| Main presenting symptom | |
| Seizure | 25 (34.2) |
| Headache | 21 (28.8) |
| Other | 27 (37.0) |
| Pathological diagnosis according to the 2007 WHO classification | |
| AA | 24 (32.9) |
| AO | 25 (34.2) |
| AOA | 24 (32.9) |
| 1p/19q status | |
| Codeletion present | 32 (43.8) |
| Codeletion absent | 41 (56.2) |
| IDH1 status | |
| Mutated | 36 (49.3) |
| Wild type | 37 (50.7) |
| 2016 WHO classification | |
| AO, IDH-mutant and 1p/19q-codeleted | 25 (34.2) |
| AA, IDH-mutant | 11 (15.1) |
| AA, IDH-wildtype | 37 (50.7) |
| MGMT promoter status | |
| Methylated | 49 (67.1) |
| Unmethylated | 24 (32.9) |
| Extent of resection | |
| Gross total resection | 43 (58.9) |
| Subtotal resection | 18 (24.7) |
| Partial resection | 8 (11.0) |
| Biopsy | 4 (5.5) |
| Chemotherapy | |
| Yes | 45 (61.6) |
| No | 28 (38.4) |
KPS, Karnofsky Performance Status; WHO, World Health Organization; AA, Anaplastic Astrocytoma; AO, Anaplastic Oligodendroglioma; AOA, Anaplastic Oligoastrocytoma; IDH, isocitrate dehydrogenase gene; MGMT, O6-methylguanine-DNA-methyltransferase gene.