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. 2017 Dec 7;10(1):58–72. doi: 10.1016/j.stemcr.2017.11.005

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Nerve Terminals from the Host Make Synaptic Contact with the Implanted hNSCs

(A) Unlabeled nerve terminal (U-NT), containing synaptic vesicles, making a synaptic-like contact (arrow) with an underlying labeled (SC121) hNSC dendrite (L-DEND). The connection may be symmetrical.

(B) Unlabeled nerve terminal (U-NT), containing synaptic vesicles, making an asymmetrical synaptic contact (arrow) with an underlying labeled (SC121) hNSC dendrite (L-DEND). This asymmetrical contact suggests an excitatory synaptic contact.