Plasminogen activator inhibitor (PAI)-1 biomarker association with primary graft dysfunction (PGD) definitions. Displayed are comparisons of PGD grade assessed between 48 and 72 hours for (A) International Society for Heart and Lung Transplantation, (B) revised, and (C) Berlin-type definitions. In this box-and-whisker plot, the box defines the upper/lower quartiles, the line depicts the median, and the whiskers the maximum and minimum values. Significance was determined using ANOVA.