Table 1.

Comparisons of regional BP values, BP _ND (k ₃/k ₄) obtained by kinetic analysis, and BP _Logan and BP _SRTM obtained by the ROI-based numerical approach and the image-derived approach, respectively. BP values obtained by reference tissue models were underestimated from BP _ND, but both Logan DVR approach and SRTM provided similar values with less error

	2TCM	BP Logan		BP SRTM
	BP ND (k 3/k 4)	ROI-based numerical approach	Image-derived approach presented	ROI-based numerical approach	Image-derived approach presented
Putamen	7.6 ± 0.37	6.7 ± 0.22	6.3 ± 0.29	6.4 ± 0.12	6.5 ± 0.16
%COV	4.9	3.3	4.6	1.9	2.5
Caudate	7.9 ± 0.49	6.8 ± 0.25	6.4 ± 0.18	6.5 ± 0.16	6.6 ± 0.16
%COV	6.2	3.7	2.8	2.5	2.4
Midbrain	1.8 ± 0.14	1.5 ± 0.11	1.4 ± 0.13	1.5 ± 0.13	1.6 ± 0.16
%COV	7.8	74.0	9.3	8.7	10.0
Thalamus	0.87 ± 0.09	0.60 ± 0.07	0.60 ± 0.06	0.50 ± 0.15	0.60 ± 0.10
%COV	10.3	11.7	10.0	30.0	16.7
Temporal	0.63 ± 0.14	0.14 ± 0.07	0.13 ± 0.07	0.12 ± 0.03	0.14 ± 0.04
%COV	22.2	50.0	53.8	25.0	28.6

2TCM: two-tissue compartment model; BP _ND: binding potential (k ₃/k ₄) obtained by kinetic analysis of the 2TCM using arterial plasma input; BP _Logan: binding potential obtained by the Logan DVR approach; BP _SRTM: binding potential obtained by the simplified reference tissue model; %COV: percent coefficient of variance; Values are mean ± s.d.