Table 2b.
Association between traditional risk factors and biomarkers and risk of coronary heart disease Values are hazard ratios and 95% confidence intervals (CI).
| HR | 95% CI | |||
|---|---|---|---|---|
| Diabetes (yes vs. no) | 3.11 | 2.51–3.86 | ||
| BMI (Kg/m2) | ||||
| < 23.15 | 1.00 | |||
| 23.16 - 25.38 | 1.50 | 1.14–1.96 | ||
| 25.39 - 28.06 | 1.86 | 1.43–2.42 | ||
| > 28.07 | 2.24 | 1.74–2.89 | ||
| Smoking habits | ||||
| Never | 1.00 | |||
| Past | 1.63 | 1.31–2.03 | ||
| Intermittent | 1.86 | 1.25–2.76 | ||
| Current | 2.09 | 1.66–2.62 | ||
| CRP (mg/L) | ||||
| < 0.70 | 1.00 | |||
| 0.71 - 1.40 | 1.25 | 0.92–1.71 | ||
| 1.41 - 2.80 | 1.82 | 1.38–2.39 | ||
| > 2.81 | 2.54 | 1.96–3.31 | ||
| Cystatin C (mg/L) | ||||
| < 0.69 | 1.00 | |||
| 0.70 -0.76 | 1.51 | 1.11–2.05 | ||
| 0.77 -0.85 | 1.92 | 1.43–2.57 | ||
| > 0.86 | 3.20 | 2.44–4.21 | ||
| LpPLA2 activity (nmol/min/mL) | ||||
| < 36.31 | 1.00 | |||
| 36.32 - 44.14 | 1.24 | 0.91–1.67 | ||
| 44.15 - 52.90 | 1.65 | 1.24–2.19 | ||
| > 52.91 | 2.47 | 1.89–3.23 | ||
| NTBNP (pg/mL) | ||||
| < 34 | 1.00 | |||
| 35–61 | 0.81 | 0.61–1.06 | ||
| 62–112 | 0.87 | 0.67–1.14 | ||
| > 113 | 1.41 | 1.10–1.80 | ||
| NTBNP (309 pg/mL) | Yes vs. No | 2.43 | 1.70–3.49 | |
CRP: C-Reactive Protein. LpPLA2: Lipoprotein-associated phospholipase A2. NTBNP: N-terminal B-type natriuretic peptide.