Table 1.
Subject demographics and cardiovascular function parameters for study participants (grouped by decompensated and compensated heart failure patients). Values shown are mean ± standard deviation. Statistical significance between groups in values, where applicable, was evaluated using an unpaired t-test.
| Decompensated (n = 13) | Compensated (n = 32) | p-value | |
|---|---|---|---|
| Gender | 11 (85%) M, 2 (15%) F | 22 (69%) M, 10 (31%) F | - |
| Height (cm) | 176.4 ± 12.1 | 173.1 ± 7.9 | 0.28 |
| Weight (kg) | 93.1 ± 15.3 | 86.9 ± 21.3 | 0.35 |
| Age (years) | 50 ± 16 | 57 ± 15 | 0.17 |
| Ejection Fraction | 20 ± 7 | 33 ± 14 | 0.003 |
| NYHA Class | 1 (8%) III, 12 (92%) IV | 4 (12%) I, 12 (38%) II, 9 (28%) III, 7 (22%) IV | - |
| Dyspnea on exertion (%) | 92 | 50 | - |
| Dyspnea at rest (%) | 77 | 31 | - |
| Orthopnea > 2 pillows (%) | 92 | 34 | - |
| Paroxysmal nocturnal dyspnea (%) | 69 | 9 | - |
| Jugular Venous Pressure (cmH2O) | 14 ± 3 | 8 ± 2 | 0.0001 |
| Pulmonary rales (%) | 92 | 19 | - |
| S3 present (%) | 46 | 9 | - |
| Bilateral leg edema (%) | 69 | 25 | - |
| Systolic blood pressure (mmHg) | 95 ± 15 | 110 ± 18 | 0.01 |
| Diastolic blood pressure (mmHg) | 65 ± 8 | 75 ± 14 | 0.02 |
| Heart Rate (bpm) | 95 ± 16 | 77 ± 16 | 0.001 |
| Pulmonary edema on chest X-ray (%) | 69 | N/A | - |
| BNP (pg/mL) | 4760 ± 450 | 380 ± 102 | 0.0001 |
| Furosemide (mg/day) | 240 ± 40 | 80 ± 20 | 0.0001 |
| Angiotensin converting enzyme inhibitors/receptor antagonists (%) | 92 | 100 | - |
| Beta-blockers (%) | 77 | 90 | - |
| Mineralocorticoid receptor blockers (%) | 77 | 100 | - |