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. 2017 Nov 1;15(1):553–561. doi: 10.3892/etm.2017.5413

Figure 5.

Figure 5.

miR-383 inhibits proliferation through the repression of ZEB2 expression. (A) The expression of ZEB2 mRNA in HEK-293T cells transfected with miR-control, miR-383, miR-NC or miR-383 inhibitor was measured. *P<0.05, **P<0.01, vs. miR-control. #P<0.05, ##P<0.01 vs. miR-NC. (B) The level of ZEB2 mRNA expression in NCU-L-4 cells transfected with miR-control, miR-383, miR-NC or miR-383 inhibitor was measured. *P<0.05, **P<0.01, vs. miR-control. #P<0.05, ##P<0.01 vs. miR-NC. (C) Cell viability was assessed in miR-control, miR-383, miR-383 plus vector and miR-383 + ZEB2 overexpression construct transfected HEK-293T cells by MTT assay at 0, 24, 48, 72 and 96 h time points. *P<0.05, **P<0.01 vs. miR-control. (D) The relative MTT assay was performed in NCU-L-4 cells. Results are presented at the mean ± standard deviation. miR-383, microRNA-383; ZEB2, zinc-finger E-box-binding homeobox 2; NC, negative control.