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Effect of Foxp3 knockdown on the HCC model of mice. Following treatment with Foxp3-short hairpin RNA, (A) western blot analysis indicated a reduced expression of Foxp3; (B) tumor volume was reduced and (C) tumor growth curves demonstrated a trend of decreased tumor volume compared with the HCC group. Foxp3, forkhead family transcription factor P3; HCC, hepatocellular carcinoma.
