Table III.
Effect of Tregs with or without Foxp3-miRNA on the proliferation of CD4+CD25− T cells.
| Index | CD4+CD25− T cells group | CD4+CD25− T cells + PBMCs group | CD4+CD25− T cells + PBMCs + Foxp3+Tregs group | CD4+CD25− T cells + PBMCs + Foxp3+Tregs group |
|---|---|---|---|---|
| OD value | 0.870±0.095 | 1.544±0.138a | 0.976±0.119b | 1.254±0.114c |
| Proliferation rate, % | – | 77.806±5.770 | 12.114±3.360b | 44.606±8.974c |
| Proliferation-inhibition ratio, % | – | – | 36.870±3.385 | 18.608±5.643c |
a
P<0.01 vs. CD4+CD25−T cells group
b
P<0.01 vs. CD4+CD25− T cells + PBMCs group
c
P<0.01 vs. CD4+CD25− T cells + PBMCs + Foxp3+Tregs group. Data are presented as mean ± standard deviation. Treg, regulatory T cell; Foxp3, forkhead family transcription factor P3; miRNA, microRNA; CD, cluster of differentiation; Foxp3+Tregs, Tregs without Foxp3-miRNA; Foxp3−Tregs, Tregs with Foxp3-miRNA; OD, optical density; PBMC, peripheral blood mononuclear cell.