Table 1.
Characteristics of HIV-infected patients on second line ART in two urban HIV clinics in Lilongwe, Malawi, means ±SD or n (%)
| Characteristic | Anemic | Not anemic | P-value† |
|---|---|---|---|
| n = 125a | n = 252a | ||
| Sex (%) | |||
| Male | 22 (17.6) | 118 (46.8) | <0.001 |
| Female | 103 (82.4) | 134 (53.2) | |
| Age, mean (SD) years | 40.5 (9.4) | 42.6 (9.6) | 0.01 |
| Total time on ART, mean (SD) years | 7.1 (2.5) | 7.5 (3.0) | 0.17 |
| Time on second line ART, mean (SD) years | 2.9 (2.0) | 3.7 (2.4) | 0.004 |
| Second line regimen (%) | |||
| Contains AZTb | 19 (15.2) | 48 (19.1) | 0.37 |
| Does not contain AZT | 106 (84.8) | 204 (81.0) | |
| CD4 count (×103cells/ul) | |||
| > 500 | 42 (35.0) | 89 (35.7) | 0.003 |
| 350–499 | 30 (24.0) | 72 (28.9) | |
| 200–349 | 23 (18.4) | 61 (24.5) | |
| < 200 | 30 (24.0) | 27 (10.8) | |
| Viral suppression (copies/ml) | |||
| < =1000 | 110 (89.4) | 230 (91.6) | 0.365 |
| > 1000 | 13 (10.6) | 21 (8.4) | |
| Body mass index, mean (SD) kg/m2 | 24.2 (5.1) | 25.1 (5.2) | 0.17 |
| Estimated glomerular filtration rate | 91.5 (31.0) | 91.8 (29.9) | 0.17 |
Anemia defined as Hb <12.0 g/dl for non-pregnant women and Hb <13.0 g/dl for men
aMissing values not included in the totals
bAZT- zidovudine
†p-value for t-test or chi-squared test as appropriate