Table 1.
Mean cholesterol levels and hypocholesterolemia frequency according to mental impairment categories
| Healthy subjects | MDD | MDD associated w/suicide attempt | P value | |
|---|---|---|---|---|
| n | 206 | 202 | 59 | -- |
| Age, years | 36.8 ± 6.6 | 37.3 ± 10.0 | 35.2 ± 10.5 | 0.363 |
| Females / Males, n (%) | 166 (80.5) /40 (19.5) | 169 (83.7) /35 (16.3) | 42 (71.2) /17 (28.8) | 0.139 |
| Obesity frequency (IMC>30 kg/m2), n (%) | 55 (26.8) | 63 (32) | 15 (25.4) | 0.431 |
| Total cholesterol serum level, mg/dl | 172.5 ± 25.3 | 167.9± 45.1 | 152.2 ± 39.0 | <.001‡,*,† |
| HDL cholesterol serum level, mg/dl | 46.0 ± 11.6 | 43.8 ± 14.5 | 46.0± 18.7 | 0.198 |
| LDL cholesterol serum level, mg/dl | 96.7 ± 29.4 | 84.0 ± 39.5 | 76.9 ± 32.5 | 0.014* |
| VLDL cholesterol serum level, mg/dl | 28.9± 14.8 | 41.2± 23.0 | 37.6± 21.3 | <.001‡,† |
| Triglyceridesserum level, mg/dl | 142.7 ± 87.1 | 208.3± 119.7 | 172.8 ± 88.1 | <.001‡,*,† |
| Hypocholesterolemia frequency (<150 mg/dl), n (%) | 28 (13.6) | 79 (38.2) | 29 (49.2) | <.001 |
MDD Major depression disorder
Values are mean ± standard deviation
*Statistically significant difference between Healthy subjects and MDD associated with suicide attempt
†Statistically significant difference between MDD and MDD associated with suicide attempt
‡Statistically significant difference between Healthy subjects and MDD