Table 2.
Analysis by gender of clinical characteristics and laboratory parameters
| Male | p value | Female | p value | |||||
|---|---|---|---|---|---|---|---|---|
| Healthy subjects | MDD | MDD associated w/suicide attempt | Healthy subjects | MDD | MDD associated w/suicide attempt | |||
| n | 40 | 36 | 17 | 166 | 171 | 42 | ||
| Age, years | 38.1 ± 6.1 | 35.8 ± 10.5 | 37.3 ± 11.9 | 0.592 | 36.5 ± 6.7 | 37.5 ± 10.0 | 34.3 ± 9.9 | 0.133 |
| Obesity frequency (IMC>30 kg/m2), n (%) | 10 (25) | 6 (17.1) | 3 (17.6) | 0.664 | 45 (27.3) | 57 (34.8) | 12 (28.6) | 0.322 |
| Total cholesterol serum level, mg/dl | 182.5 ± 42.5 | 164.8 ± 48.6 | 140.2 ± 32.1 | 0.002 ‡,* | 170.1 ± 18.4 | 168.5 ± 44.4 | 157.1 ± 40.8 | 0.017* |
| HDL cholesterol serum level, mg/dl | 46.4 ± 14.5 | 41.7 ± 15.8 | 44.1 ± 12.4 | 0.566 | 45.8 ± 10.2 | 44.2 ± 14.2 | 46.8 ± 20.9 | 0.301 |
| LDL cholesterol serum level, mg/dl | 100.8 ± 35.9 | 71.2 ± 37.2 | 71.7 ± 24.5 | 0.011 ‡ | 94.8 ± 26.2 | 86.7 ± 39.5 | 78.9 ± 35.3 | 0.165 |
| VLDL cholesterol serum level, mg/dl | 30.9 ± 17.0 | 55.4 ± 33.4 | 29.8 ± 10.1 | 0.002 ‡,† | 28.1 ± 13.9 | 38.1 ± 18.9 | 34.9 ± 18.7 | 0.004 ‡ |
| Triglycerides serum level, mg/dl | 137.7 ± 66.9 | 277.1 ± 167.2 | 157.6 ± 60.2 | <.001‡,† | 143.9 ± 91.4 | 193.7 ± 101.8 | 179.0 ± 97.2 | <.001‡,* |
| Hypocholesterolemia frequency (<150 mg/dl), n (%) | 8 (20) | 17 (47.2) | 9 (52.9) | 0.015 | 20 (12) | 62 (36.3) | 20 (47.6) | <.001 |
Values are mean ± standard deviation
*Statistically significant difference between Healthy subjects and MDD associated with suicide attempt
†Statistically significant difference between MDD and MDD associated with suicide attempt
‡Statistically significant difference between Healthy subjects and MDD