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ANXA11 downregulation inhibits the AKT/GSK-3β signaling pathway in GC cell lines. (A, B) The protein expression levels of AKT1, phosphor-Akt1/2/3Thr308/309/305, GSK-3β, phosphor-GSK-3βSer9, CyclinD1, and PCNA were examined by WB in AGS and SGC-7901 cell lines, and the expression levels of AKT1, phosphor-Akt1/2/3Thr308/309/305, GSK-3β, phosphor-GSK-3βSer9, CyclinD1, and PCNA were significantly decreased in the ANXA11-siRNA group compared to the NC group. * P<0.05.
