Fig. 2.

a, c) The familial relative risk (FRR) as a function of the individual relative risk (IRR) defined in terms of the dichotomous model in Expression (1) and (2), assuming one or two diseased family members, respectively. b, d) The IRR as a function of the FRR. 50% (q=0.5) and 80% (q=0.8) of the population belong to the high-risk group in panels a, b) and c, d), respectively