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a) 65 μm OD side-firing optical fiber with three windows tested in agar model of brain tissue; b) Side-view of the same fiber inserted in a swine brain slice shows a larger illuminated volume inside the tissue; c) Side-view of unmodified 65 μm fiber in a swine brain slice shows smaller illuminated volume localized at the tip of the fiber. Illumination sites in the swine brain were observed through ~ 0.5 cm layer of brain tissue.
