Table 1.
Patients characteristics (n = 63)
| Clinical profile | |
| Female/male [n (%)] | 32 (50.2) / 31 (49.8) |
| Age (years) | 66.1 ± 1.7 |
| BMI (kg/m2) | 26.0 (18.0–43.0) |
| NT-proBNP | |
| NT-proBNP at rest (pg/ml) | 1414 (38–13,538) |
| NT-proBNP at exercise (pg/ml) | 1500 (42–14,365) |
| NT-proBNP ratio | 6.95 (0.09–60.60) |
| ΔNT-proBNP (pg/ml) | 77 (0–1160) |
| 6-min walking test | |
| Distance (m) | 300 (100–570) |
| % of norm (%) | 63.0 ± 3.2 |
| Breaks (n) | 0 (0–4) |
| Borg scale points (1–10) | 4 (0–10) |
| Right heart catheterisation | |
| Mean PAP (mmHg) | 39.0 ± 1.5 |
| Cardiac output (l/min) | 4.10 (2.30–8.90) |
| Cardiac index (l/min/m2) | 2.35 ± 0.10 |
| PVR (Wood Units) | 7.45 (3.04–14.20) |
| Mean RAP (mmHg) | 6.00 (1.00–20.00) |
| SvO2 (%) | 61.1 ± 1.04 |
| Lung function | |
| DLCO (%) | 52.6 ± 3.30 |
| PaO2 at rest (mmHg) | 58.0 ± 1.70 |
| PaO2 at peak exercise (mmHg) | 58.0 ± 2.27 |
| Cardiopulmonary exercise testing | |
| Work capacity (watts) | 45.0 (25–122) |
| VO2 (ml/min) | 941 ± 41.5 |
| VO2 (ml/min/kg) | 12.7 ± 0.5 |
| AT (ml/min/kg) | 9.43 ± 0.37 |
| O2 pulse at peak exercise (ml/min/beat) | 8.46 ± 0.34 |
| Ve (L/min) | 50.8 ± 2.23 |
| Ve/VO2 | 39.0 (25.0–77.0) |
| Ve/VCO2 | 44.0 (28.0–87.0) |
| AaDO2 (mmHg) | 48.1 ± 2.2 |
| Vd/Vt (%) | 36.7 ± 1.7 |
| Ve/VCO2 Slope | 39.5 (14.3–107) |
When not stated otherwise, data are presented as mean ± SEM or as median (range)