Table 3.

Correlation of NT-proBNP and ∆ NT-proBNP with hemodynamics and exercise capacity at rest and at peak exercise

		NT-proBNP at rest				NT-proBNP at peak exercise		∆ NT-proBNP
		level		ratio		level		level
	n	r	p	r	p	r	p	r	p
6MWT
Distance (m)	61	−0.507	<0.001	−0.328	0.010	−0.490	<0.001	−0.256	0.047
% of norm	61	−0.546	<0.001	−0.481	<0.001	−0.534	<0.001	−0.310	0.015
Breaks (n)	63	0.556	<0.001	0.484	<0.001	0.541	<0.001	0.183	0.152
Borg scale	63	0.271	0.032	0.245	0.053	0.260	0.039	0.033	0.800
Hemodynamics
Mean PAP (mmHg)	63	0.341	0.006	0.521	0.001	0.335	0.007	0.110	0.391
Cardiac output (l/min)	62	−0.322	0.011	−0.228	0.074	−0.325	0.01	−0.215	0.093
Cardiac index (l/min/m²)	36	−0.384	0.021	−0.360	0.031	−0.384	0.021	−0.248	0.145
PVR (wood units)	56	0.359	0.007	0.476	<0.001	0.361	0.006	0.226	0.094
Mean RAP (mmHg)	57	0.231	0.083	0.281	0.034	0.220	0.100	0.149	0.269
SVO₂ (%)	61	−0.530	<0.001	−0.443	<0.001	−0.515	<0.001	−0.208	0.107
Lung function
DLCO (%)	44	−0.332	0.028	−0.270	0.077	−0.314	0.038	−0.182	0.238
PaO₂ at rest (mmHg)	63	−0.312	0.013	−0.233	0.066	−0.295	0.019	−0.029	0.824
PaO₂ at exercise (mmHg)	63	−0.221	0.081	−0.174	0.171	−0.202	0.113	−0.068	0.599
CPET
Work (watts)	63	−0.438	<0.001	−0.280	0.026	−0.410	0.001	−0.074	0.567
VO₂ (ml/min)	63	−0.492	<0.001	−0.335	0.007	−0.473	<0.001	−0.136	0.289
VO₂/kg	63	−0.514	<0.001	−0.436	<0.001	−0.490	<0.001	−0.193	0.130
AT (ml/min/kg)	48	−0.307	0.034	−0.335	0.062	−0.272	0.020	−0.165	0.263
O₂ pulse (ml/min/beat)	62	−0.362	0.004	−0.290	0.022	−0.356	0.004	−0.089	0.491
Ve (l/min)	63	−0.024	0.853	0.092	0.472	−0.007	0.955	0.183	0.151
Ve/VO₂	49	0.479	<0.001	0.398	0.005	0.463	0.001	0.241	0.096
Ve/VCO₂	49	0.465	0.001	0.361	0.011	0.446	0.001	0.219	0.131
AaDO₂ (mmHg)	63	0.452	<0.001	0.395	0.001	0.442	<0.001	0.320	0.011
Vd/Vt (%)	62	0.349	0.005	0.296	0.019	0.335	0.008	0.130	0.314
Ve/VCO₂ slope	62	0.471	<0.001	0.435	<0.001	0.466	<0.001	0.330	0.009