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. 2018 Jan;59(1):132–143. doi: 10.1167/iovs.17-22454

Figure 4.

Figure 4

Strong concordance of gene signature of ICG-001 in UM with signatures of ICG-001 and p300 inhibitor in other cancers. Gene set enrichment analysis shows high concordance between the ICG-001 signature from UM and the transcriptomic footprints of ICG-001 (A–D) as well as with the signature of C646 (E–H), a small molecule inhibitor of p300, derived from the HCT116 (colon cancer) and PANC1 (pancreatic cancer) cell lines (GSE64038).