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. 2018 Jan 15;155:17. doi: 10.1186/s41065-018-0055-7

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The multi-step strategy used in this study. First, significantly changed miRNAs in GSE66607 (cells for miRNA in MCF-7/TamR vs MCF-7) and GSE37405 (tissues for breast cancer tissues) were identified. Second, GSE37405 and Kaplan-Meier Plotter Database (KMPD) for miRpower of breast cancer as the validated set were used to screen overlapped miRNAs in step 1 that related to overall survival. Third, for the target mRNA genes, KMPD, and Gene Expression Profiling Interactive Analysis (GEPIA), were used to reveal the relationship between target genes and overall survival