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In vitro dialysis release study of BH from formulations: (a) BH solution, (b) conventional BH microsphere, and (c) BMEM. The cumulative drug release (%) is plotted against time (h). Values are presented as the mean ± SD (n=5). SEM micrographs of BMEM: (A) microsphere before release process and (B) microsphere after release process.
Abbreviations: BH, betaxolol hydrochloride; BMEM, betaxolol hydrochloride encapsulated microsphere; SEM, scanning electron microscopy.
