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. 2017 Nov 14;6(12):1869–1875. doi: 10.1242/bio.026005

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© 2017. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 4. — BIP-V5 inhibits Bax activation in bleomycin-induced pneumopathy and bleomycin-treated A549 cells. (A) The expression of the Bax-activated form of mouse bleomycin-induced pneumopathy homogenate lung on day 7. (B) The expression of Bax-activated form of A549 cells under BLM treatment. A549 cells were treated with normal saline or BLM (120 mU/ml) for 24 h. BIP-V5 (200 µM) was pre-dosed 1 h before the administration of saline or BLM. Data were collected from three separate experiments and are expressed as the mean±s.e.m. *P<0.05, **P<0.01. TCL, total cell lysate; IP, immunoprecipitation.